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Year : 2017  |  Volume : 8  |  Issue : 3  |  Page : 116-118

Acquired amegakaryocytic thrombocytopenic purpura with literature review

1 Department of Hematology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India
2 Department of Internal Medicine, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India
3 Department of Pathology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Prabu Pandurangan
Consultant Hematologist, Apollo Main Hospital, Greams Road, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/joah.joah_18_17

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Acquired amegakaryocytic thrombocytopenic purpura (AATP) is an uncommon disorder with thrombocytopenia and selectively suppressed megakaryopoiesis, often mistaken as immune thrombocytopenic purpura (ITP). It usually does not respond to steroids, and bone marrow examination shows complete absence of megakaryocytes. The treatment and prognosis of AATP vary greatly from ITP; therefore, it is important to diagnose and treat this condition early, as it can progress rapidly to complete bone marrow failure. In this case report, we report a patient with AATP responded well to cyclosporine therapy.

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