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Year : 2017  |  Volume : 8  |  Issue : 4  |  Page : 159

Back to basics: Dimorphic anemia and peripheral blood smear examination

Department of Pathology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

Date of Web Publication12-Jan-2018

Correspondence Address:
Dr. Ashok Singh
Department of Pathology, All India Institute of Medical Sciences, Rishikesh - 249 203, Uttarakhand
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/joah.joah_64_17

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How to cite this article:
Singh A. Back to basics: Dimorphic anemia and peripheral blood smear examination. J Appl Hematol 2017;8:159

How to cite this URL:
Singh A. Back to basics: Dimorphic anemia and peripheral blood smear examination. J Appl Hematol [serial online] 2017 [cited 2023 Sep 30];8:159. Available from: https://www.jahjournal.org/text.asp?2017/8/4/159/223180

We read with great interest the article “Clinico-hematological profile of dimorphic anemia” by Garg et al.[1] Dimorphic anemia, morphologically characterized by two cell population, strongly suggests a dual deficiency of iron and Vitamin B12/folate. Other causes of dimorphic anemia include iron deficiency anemia responding to iron therapy, after transfusion of normal blood to a patient with a hypochromic anemia, sideroblastic anemia, macrocytic anemia posttransfusion, the unmasking of iron deficiency following treatment of megaloblastic anemia, and delayed transfusion reactions. Nutritional anemia, which is an important cause of dimorphic anemia, is a significant problem worldwide. Prevalence of anemia is high in developing countries, especially among women.[2] Similarly, the authors have noted that although dimorphic anemia is common in developing countries, yet it is an undermined entity.[1]

The authors have also emphasized on the role of complete hemogram and peripheral blood smear examination.[1] In spite of significant developments in the diagnostic modalities, peripheral blood smear examination remains an invaluable component of hematology.[3] An accurate peripheral blood smear interpretation can help in diagnosing vast spectrum of hematologic disorders, guide further testing, and patient management.[4] Thus, in low resource settings, complete hemogram and peripheral blood smear examination are basic yet highly informative diagnostic tools for screening, diagnosis and monitoring of anemia.

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  References Top

Garg P, Dey B, Deshpande AH, Bharti JN, Nigam JS. Clinico-hematological profile of dimorphic anemia. J Appl Hematol 2017;8:123-4.  Back to cited text no. 1
  [Full text]  
Bentley ME, Griffiths PL. The burden of anemia among women in India. Eur J Clin Nutr 2003;57:52-60.  Back to cited text no. 2
Adewoyin AS, Nwogoh B. Peripheral blood film – A review. Ann Ib Postgrad Med 2014;12:71-9.  Back to cited text no. 3
Garg P, Deshpande AH, Dey B, Ojha P. A study of the peripheral smears in a tertiary care teaching hospital in Andaman & Nicobar Islands. Int J Health Sci Res 2017;7:22-7.  Back to cited text no. 4


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