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Year : 2020  |  Volume : 11  |  Issue : 2  |  Page : 77-79

Valproic acid for the treatment of refractory pediatric primary bone anaplastic large-cell lymphoma: A case report and literature review

1 Department of Hematology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
2 Department of Hematology, King Abdulaziz University Hospital; King Faisal Special Hospital and Research Center, Jeddah, Saudi Arabia

Correspondence Address:
Dr. Ali H Algiraigri
Department of Hematology, King Abdulaziz University Hospital, Jeddah 22252
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/joah.joah_3_20

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Primary bony anaplastic large-cell lymphoma is quite rare in children but potentially life-threatening lymphoma. Such disease is challenging and often carries a poor prognosis. Here, we report a patient who presented with an aggressive bony lymphoma and failed to respond to conventional chemotherapy; however, he had a robust response to valproic acid, which changed his status from hopeless palliative case to a success story and allowed him to complete his intended chemotherapy protocol.

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