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Year : 2022  |  Volume : 13  |  Issue : 3  |  Page : 154-156

Cold agglutinin disease in COVID-19 causing severe intravascular hemolysis

1 Department of Pathology, Vijaya Medical and Educational Trust, Chennai, Tamil Nadu, India
2 Department of Medicine, Vijaya Medical and Educational Trust, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Sarah Grace Priyadarshini
27 Vinayakar Koil Street, Little Mount, Chennai - 600 015, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/joah.joah_75_21

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Cold agglutinin disease (CAD) is a distinct type of acquired immune hemolytic anemia. It can be idiopathic (primary) or secondary to infections, neoplasms and autoimmune diseases. Mycoplasma pneumonia and EBV are the infections commonly associated with secondary CAD. In the current COVID-19 pandemic, there are very few case reports showing an association between CAD and COVID-19.

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