• Users Online: 276
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 


 
 Table of Contents  
ORIGINAL ARTICLE
Year : 2023  |  Volume : 14  |  Issue : 1  |  Page : 12-16

Blastic Plasmacytoid Dendritic Cell Neoplasm: A 10-year Bibliometric Study


1 Academic Department, Sociedad Científica San Fernando, Universidad Nacional Mayor De San Marcos; Academic Department, Grupo Peruano De Investigación Epidemiológica, Unidad Para La Generación Y Síntesis De Evidencias En Salud, Universidad San Ignacio De Loyola, Lima, Peru
2 Academic Department, Direccion De Investigación, Universidad Privada Del Norte, Lima, Peru
3 Academic Department, Faculty of Medical Technology, Universidad Nacional Federico Villarreal, Lima, Peru
4 Academic Department, Universidad Nacional Mayor De San Marcos, Lima, Peru
5 Postgraduate Department, Vicerrectorado de Investigacion, Universidad San Ignacio de Loyola, Lima, Peru

Date of Submission29-Aug-2022
Date of Decision06-Sep-2022
Date of Acceptance10-Dec-2022
Date of Web Publication17-Feb-2023

Correspondence Address:
Dr. Frank Mayta-Tovalino
Department of Postgraduate, Universidad San Ignacio de Loyola, Av. la Fontana 550, La Molina 15024
Peru
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/joah.joah_81_22

Rights and Permissions
  Abstract 

INTRODUCTION: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological disease. There is an incidence. We aimed to evaluate the scientometrics characteristics of the scientific production on BPDCN between 2011 and 2020.
METHODOLOGY: A cross-sectional and retrospective bibliometric study was performed. The search was executed in the Scopus database. Data were extracted based on a formula developed using thesaurus MeSH (Medline) and Emtree (Embase) terms. The retrieved papers received 11.2 citations per paper. Four of the ten most productive authors were from the United States. The institution with the highest impact (1064 citations) and the highest scientific output (46 papers) was the University of Texas MD Anderson Cancer Center (United States).
RESULTS: The journal “Movement Disorders” rated first with 18 articles and 643 citations in terms of productivity and impact, and articles published in Q1 journals surpassed the remaining quartiles. The most cited articles had national collaboration. Conclusion the number of papers on BPDCN has been rising, yet journals with a higher quality tend to keep the similar publication rates, although they have shown a slight increase in the recent years.
CONCLUSIONS: High-income countries' international collaboration is crucial for increasing publications impact; hence, greater collaborations between researchers and institutions from countries around the world are needed to expand knowledge on this subject.

Keywords: Bibliometric analysis, Blastic plasmacytoid dendritic cell neoplasm, cancer


How to cite this article:
Quispe-Vicuna C, Cabanillas-Lazo M, Barja-Ore J, Mauricio-Vilchez C, Guerrero ME, Munive-Degregori A, Mayta-Tovalino F. Blastic Plasmacytoid Dendritic Cell Neoplasm: A 10-year Bibliometric Study. J Appl Hematol 2023;14:12-6

How to cite this URL:
Quispe-Vicuna C, Cabanillas-Lazo M, Barja-Ore J, Mauricio-Vilchez C, Guerrero ME, Munive-Degregori A, Mayta-Tovalino F. Blastic Plasmacytoid Dendritic Cell Neoplasm: A 10-year Bibliometric Study. J Appl Hematol [serial online] 2023 [cited 2023 Jun 4];14:12-6. Available from: https://www.jahjournal.org/text.asp?2023/14/1/12/369845


  Introduction Top


Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological disease with an incidence of about 0.04/100,000 inhabitants worldwide, and it usually occurs in elderly people.[1] The main clinical manifestations are cutaneous involvement, either through plaques and nodules or through violaceous skin lesions; it can also develop spinal cord infiltration or in some cases extramedullary infiltration.[2],[3] Although it has been related with other hematologic neoplasms such as myelodysplastic syndrome, its etiology has not yet been confirmed.[4]

The BPDCN diagnosis is based on immunohistochemistry, with a positive result for four of the five main surface markers: CD4, CD56, CD123, TCL1, and CD303.[5] Although there is no standardized treatment, chemotherapy with high-dose methotrexate with asparaginase, acute myeloid leukemia (AML), and acute lymphoid leukemia type showed improved survival and remission over other treatments.[3]

The scientific contribution of researchers, institutions, a specific region, or a certain field has been measured using bibliometric analysis. Furthermore, it can allow research to be oriented toward previously unaddressed areas.[6],[7],[8],[9] In addition, they have also been used to determine the citations influence between journals and to study the collaborative contribution in an multidisciplinary subject.[9],[10],[11],[12] Although no previous bibliometric studies of BPDCN have been developed, previous bibliometric analyses of other hematologic malignancies have been reported. On AML, it was reported that between 1999 and 2018, the genetic domain was one of the most studies.[13] In addition, regarding the hematological tumor microenvironment, immunotherapy was reported to be the current approach with the most investigations.[14] The results of this study could be useful for future research on BPDCN, not only identifying which areas are the most investigated but also to identify potential collaborators and journals. In addition, assessing trends in BPDCN research may promote the development of future advances in the field of treatments or new diagnostic methods.

Therefore, the purpose of this study was to evaluate through a bibliometric analysis of the trends, the scars and impact of publications related to BPDCN between 2011 and 2020.


  Methodology Top


Manuscript metadata were downloaded from Scopus. It was decided to work with this database because it is one of the most prestigious and important at the international and multidisciplinary level.[15] The SciVal software was selected to complete the bibliometric analyses and to calculate the different metrics.

The MeSH terms in PubMed and the Emtree terms in Embase were used. With the help of the Boolean operators “AND” and “OR,” the advanced search strategy was established: TITLE-ABS-KEY (“BPDCN” OR “Monomorphic NK-cell lymphoma” OR “Lymphoblastoid variant of NK-cell lymphoma” OR (“blastic*” AND “agranul*”) OR “hematodermic neoplasm” OR “BPDCN”).

For the sake of accuracy, the search was limited to journals in the subject area “Medicine.” Letters to the editor, articles in press, and errata were excluded. The study period limit was from 2011 to 2020.

Statistical analysis

The search was carried out on September 19, 2021. The data were saved from Scopus in.CSV format and then exported to the SciVal tool. The most productive journals and authors publishing scientific articles on BPDCN, number of articles, number of institutions, collaboration, citations per publication, and CiteScore were analyzed.[16] Finally, VOSviewer (version 1.6.10, Leiden University, The Netherlands) was selected to evaluate the co-occurrence and co-citation collaborative networks.


  Results Top


A total of 486 articles were selected from SciVal: a total of 2662 authors, 5463 citations, and a mean of 11.2 citations per article. Most of the selected papers were published in these main subcategories: hematology (n = 203; 41.8%), oncology (n = 135; 27.8%), dermatology (n = 81; 16.7%), pathology and forensic medicine (n = 68; 14.0%), and general medicine (n = 63; 13.0%).

Top 10 most productive authors

[Table 1] shows the most productive authors on the topic of BPDCN. Pemmaraju with the affiliation University of Texas MD Anderson Cancer Center had the highest number of published manuscripts[17] together with the highest number of citations (840), followed by author Lane with 16 published studies.
Table 1: Top 10 authors publishing on Blastic plasmacytoid dendritic cell neoplasm

Click here to view


The principal institutions with the highest number of articles are shown in [Table 2]. The University of Texas MD Anderson Cancer Center (USA) was the institution with the highest academic production (46) and 23.1 citations per paper. Finally, the following institutions with more academic production were the Dana-Farber Cancer Institute (USA) and Harvard University (USA), respectively.
Table 2: Top 10 institutions on Blastic plasmacytoid dendritic cell neoplasm

Click here to view


[Table 3] shows the main journals with the highest number of BPDCN publications. The top three most productive journals were Blood, Annals of Hematology and Haematologica with an average of 18, 13 and 13 articles respectively. However, in terms of the highest citation, only the former keeps its place (643). The American Journal of Hematology obtained a great number of citations citations/paper.
Table 3: Bibliometric indicators of impact and production on Blastic plasmacytoid dendritic cell neoplasm

Click here to view


Furthermore, in accordance with the CiteScore, [Table 4] shows the amount of articles by journal quartiles published between 2011 and 2020. The high concentration of the first quartile manuscripts suggests the high research quality.
Table 4: Documents published according to CiteScore quartile on blastic plasmacytoid dendritic cell neoplasm

Click here to view


[Table 5] shows the collaboration type with bibliometric indicators. The majority of the articles had only institutional collaboration (n = 201; 42.0%), followed by only national collaboration (n = 187; 39.0%) and international collaboration (n = 61; 12.7%). However, international collaboration (1641; 26.9 citations) exceeds both national (2397; 12.8) and institutional (1326; 6.6) in terms of impact. The remaining papers belong to the “single authorship” or “no collaboration” category (n = 30; 6.3%).
Table 5: Type of collaboration on Blastic plasmacytoid dendritic cell neoplasm

Click here to view



  Discussion Top


In the recent years, there has been a significant augmentation in the number of publications related to BPDCN. However, this is the first worldwide bibliometric analysis on this field. This research shows that the study impact is mainly conveyed through certain indicators of collaboration, impact, and quantity or production. Bibliometric analyses allow a broad evaluation of research, especially in specialized fields of knowledge.[18],[19] Scopus is a database that allows this broad analysis, since it has an extensive repertoire of tools for the description of citations and authors, and in turn, has a large number of papers and references compared to other databases such as the Web of Science, Dimensions, or Crossref, thus providing a broader perspective.[20]

The subcategories with the highest number of articles are hematology and oncology, which agrees with the previous result of Zhong et al. in a bibliometric analysis of a topic similar to BPDCN, reported that the topics with the highest number of publications are hematology, oncology, and immunology.[21]

The author with more articles and citations than any other in BPDCN was Pemmaraju and among his most recent articles he has published are reviews regarding treatment for this neoplasm.[22],[23] Although no previous bibliometric studies on BPDCN have been identified, Noor et al. mentioned the influence of social networks[24] on the dissemination of publications in oncology and hematology.[17],[25] The main reason is because the author has recently published many reviews on BPDCN therapies in the first quartile (Q1) journals, which would increase their possibility of being cited. Regarding the country of origin, half of the 10 authors with the highest academic production are from the United States. This could be explained by the fact that previous bibliometric studies of other hematologic malignancies[13] or myeloma[26] have reported many articles from that country.

Regarding the top 10 productive institutions, the US institutions reported the highest productivity. The institution with the highest frequency of citations, publications, and authors was the University of Texas MD Anderson Cancer Center. This result was also reported on bibliometric research by Iqbal et al. They found that this institution was the most productive in the immunotherapy childhood leukemia field, which is part of a similar line of research to BPDCN. In addition, it should be mentioned that the Establishment français du sang in France was the institution with more citations per paper than any other.

The journal “Blood” has the highest number of documents (18) and citations (643). This is consistent with the results of other bibliometric study on acute myeloid leukemia which reported the highest number of publications and h-index.[13] It can also be added that in another bibliometric analysis both Blood and the British Journal of Haematology, reported having had greater publication regarding immunotherapy in childhood leukemia.[21] This has been an area quite studied for BPDCN, being this latter a subtype of leukemia,[27] and having reported cases of occurrence in pediatric population.[28] Furthermore, half of the articles were presented in Q1 journals. This confirmed the scientific community interest toward BPDCN. Regarding the type of collaboration, institutional-only publications predominated over the rest, and the highest was the amount of citations with the national collaboration. However, the international collaboration had a greater impact on BPDCN research. The international collaboration should be encouraged to address new research horizons and identify new priorities, as well as to exchange relevant information.

Regarding the limitations and strengths of this study: first, the inclusion of only the most recent principal publications (2011–2020), which represents more than 80% of all articles on Scopus; second, articles published in journals not indexed in Scopus may have been omitted which does not reflect the total of articles on the area; although it should be clarified that Scopus presents a strict peer review process when including a journal, this to ensure high quality for research.[20],[29] Nevertheless, this is the first bibliometric study on BPDCN.


  Conclusions Top


The number of papers on BPDCN has been increasing in the last decade, especially for high-quality journals. The national and institutional collaborations are important for the publications impact. Researchers and institutions from around the world need to joint efforts to ensure networking and future research on this topic.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Guru Murthy GS, Pemmaraju N, Atallah E. Epidemiology and survival of blastic plasmacytoid dendritic cell neoplasm. Leuk Res 2018;73:21-3.  Back to cited text no. 1
    
2.
Venugopal S, Zhou S, El Jamal SM, Lane AA, Mascarenhas J. Blastic plasmacytoid dendritic cell neoplasm-current insights. Clin Lymphoma Myeloma Leuk 2019;19:545-54.  Back to cited text no. 2
    
3.
Garnache-Ottou F, Vidal C, Biichlé S, Renosi F, Poret E, Pagadoy M, et al. How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients? Blood Adv 2019;3:4238-51.  Back to cited text no. 3
    
4.
Kong QT, Zhang M, Sang H, Chen J, Yan W, Hu W, et al. Blastic plasmacytoid dendritic cell neoplasm of the skin associated with myelodysplastic syndrome. Dermatol Online J 2014;21:18-21.  Back to cited text no. 4
    
5.
Sweet K. Blastic plasmacytoid dendritic cell neoplasm: Diagnosis, manifestations, and treatment. Curr Opin Hematol 2020;27:103-7.  Back to cited text no. 5
    
6.
Yazdani K, Nejat S, Rahimi-Movaghar A, Ghalichee L, Khalili M. Scientometrics: Review of concepts, applications, and indicators. Iran J Epidemiol 2015;10:78-88.  Back to cited text no. 6
    
7.
Miller C, Wenzel V. On the quality of bibliometric analyses. Anaesthesist 2021;70:863-5.  Back to cited text no. 7
    
8.
Mayta-Tovalino F, Pacheco-Mendoza J, Diaz-Soriano A, Perez-Vargas F, Munive-Degregori A, Luza S. Bibliometric study of the National scientific production of all Peruvian schools of dentistry in Scopus. Int J Dent 2021;2021:5510209.  Back to cited text no. 8
    
9.
Quincho-Lopez A, Pacheco-Mendoza J. Research trends and collaboration patterns on polymyxin resistance: A bibliometric analysis (2010-2019). Front Pharmacol 2021;12:702937.  Back to cited text no. 9
    
10.
Machado RD, Vargas-Quesada B, Leta J. Intellectual structure in stem cell research: exploring Brazilian scientific articles from 2001 to 2010. Scientometrics 2016;106:525-37.  Back to cited text no. 10
    
11.
Liu P, Xia H. Structure and evolution of co-authorship network in an interdisciplinary research field. Scientometrics 2015;3:101-34.  Back to cited text no. 11
    
12.
Makkizadeh F, Sa'adat F. Bibliometric and thematic analysis of articles in the field of infertility (2011-2015). Int J Reprod Biomed 2017;15:719-28.  Back to cited text no. 12
    
13.
Seo B, Kim J, Kim S, Lee E. Bibliometric analysis of studies about acute myeloid leukemia conducted globally from 1999 to 2018. Blood Res 2020;55:1-9.  Back to cited text no. 13
    
14.
Chen P, Du Z, Wang J, Liu Y, Zhang J, Liu D. A bibliometric analysis of the research on hematological tumor microenvironment. Ann Transl Med 2021;9:1337.  Back to cited text no. 14
    
15.
Falagas ME, Pitsouni EI, Malietzis GA, Pappas G. Comparison of pubmed, scopus, web of science, and Google scholar: Strengths and weaknesses. FASEB J 2008;22:338-42.  Back to cited text no. 15
    
16.
Roldan-Valadez E, Salazar-Ruiz SY, Ibarra-Contreras R, Rios C. Current concepts on bibliometrics: A brief review about impact factor, Eigenfactor score, citeScore, SCImago journal rank, source-normalised impact per paper, H-index, and alternative metrics. Ir J Med Sci 2019;188:939-51.  Back to cited text no. 16
    
17.
Pemmaraju N, Thompson MA, Mesa RA, Desai T. Analysis of the use and impact of twitter during American society of clinical oncology annual meetings from 2011 to 2016: Focus on advanced metrics and user trends. J Oncol Pract 2017;13:e623-31.  Back to cited text no. 17
    
18.
van Eck NJ, Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics 2010;84:523-38.  Back to cited text no. 18
    
19.
Ellegaard O, Wallin JA. The bibliometric analysis of scholarly production: How great is the impact? Scientometrics 2015;105:1809-31.  Back to cited text no. 19
    
20.
Visser M, van Eck NJ, Waltman L. Large-scale comparison of bibliographic data sources: Scopus, web of science, dimensions, crossref, and microsoft academic. Quant Sci Stud 2021;2:20-41.  Back to cited text no. 20
    
21.
Zhong Q, Li BH, Zhu QQ, Zhang ZM, Zou ZH, Jin YH. The top 100 highly cited original articles on immunotherapy for childhood Leukemia. Front Pharmacol 2019;10:1100.  Back to cited text no. 21
    
22.
Economides MP, Konopleva M, Pemmaraju N. Recent developments in the treatment of blastic plasmacytoid dendritic cell neoplasm. Ther Adv Hematol 2019;10:1-9.  Back to cited text no. 22
    
23.
Economides MP, Rizzieri D, Pemmaraju N. Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN). Curr Hematol Malig Rep 2019;14:515-22.  Back to cited text no. 23
    
24.
Noor S, Guo Y, Shah SH, Hamad S, Saqib M. Research synthesis and thematic analysis of twitter through bibliometric analysis. Int J Semant Web Inf Syst 2020;16:88-109.  Back to cited text no. 24
    
25.
Pemmaraju N, Thompson MA, Qazilbash M. Disease-specific hashtags and the creation of Twitter medical communities in hematology and oncology. Semin Hematol 2017;54:189-92.  Back to cited text no. 25
    
26.
Andersen JP, Bøgsted M, Dybkær K, Mellqvist UH, Morgan GJ, Goldschmidt H, et al. Global myeloma research clusters, output, and citations: A bibliometric mapping and clustering analysis. PLoS One 2015;10:e0116966.  Back to cited text no. 26
    
27.
Sapienza MR, Pileri A, Derenzini E, Melle F, Motta G, Fiori S, et al. Blastic Plasmacytoid dendritic cell neoplasm: State of the art and prospects. Cancers (Basel) 2019;11:595.  Back to cited text no. 27
    
28.
Liao C, Hu NX, Song H, Zhang JY, Shen DY, Xu XJ, et al. Pediatric blastic plasmacytoid dendritic cell neoplasm: Report of four cases and review of literature. Int J Hematol 2021;113:751-9.  Back to cited text no. 28
    
29.
Baas J, Schotten M, Plume A, Côté G, Karimi R. Scopus as a curated, high-quality bibliometric data source for academic research in quantitative science studies. Quant Sci Stud 2020;1:377-86.  Back to cited text no. 29
    



 
 
    Tables

  [Table 1], [Table 2], [Table 3], [Table 4], [Table 5]



 

Top
 
 
  Search
 
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

 
  In this article
Abstract
Introduction
Methodology
Results
Discussion
Conclusions
References
Article Tables

 Article Access Statistics
    Viewed1693    
    Printed38    
    Emailed0    
    PDF Downloaded211    
    Comments [Add]    

Recommend this journal


[TAG2]
[TAG3]
[TAG4]