Journal of Applied Hematology

CASE REPORT
Year
: 2019  |  Volume : 10  |  Issue : 4  |  Page : 146--148

Successful use of fondaparinux for perioperative bridging in a patient with a mechanical heart valve and heparin-induced thrombocytopenia


CR Pruthvi, Krishna Prasad, Dinakar Bootla, V Krishna Santosh, Parag Barwad 
 Department of Cardiology, Post Graduate Institute for Medical Education and Research, Chandigarh, India

Correspondence Address:
Dr. Parag Barwad
Department of Cardiology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012
India

The mechanical heart valve prosthesis is a thrombotic state requiring anticoagulation at therapeutic doses. Heparin-induced thrombocytopenia (HIT) is both a thrombotic and bleeding state which has a high chance of recurrence when heparin is reinitiated. Unfractionated heparin and low molecular-weight heparin are the standard of care for bridging therapy that are on anticoagulation with warfarin for various reasons. However, perioperative bridging in patients having a prior history of HIT is often elusive. We successfully used fondaparinux as a bridging agent for warfarin in a mitral valve replacement patient with a history of HIT.


How to cite this article:
Pruthvi C R, Prasad K, Bootla D, Santosh V K, Barwad P. Successful use of fondaparinux for perioperative bridging in a patient with a mechanical heart valve and heparin-induced thrombocytopenia.J Appl Hematol 2019;10:146-148


How to cite this URL:
Pruthvi C R, Prasad K, Bootla D, Santosh V K, Barwad P. Successful use of fondaparinux for perioperative bridging in a patient with a mechanical heart valve and heparin-induced thrombocytopenia. J Appl Hematol [serial online] 2019 [cited 2022 Sep 29 ];10:146-148
Available from: https://www.jahjournal.org/article.asp?issn=1658-5127;year=2019;volume=10;issue=4;spage=146;epage=148;aulast=Pruthvi;type=0